Parvovirus B19 Infection with parvovirus B19 is usually mild, and the symptoms often include a rash on the cheeks, known as “slapped cheek” rash in children, and joint pain in adults. Complications may arise in people with underlying blood disorders or a weakened immune system. Infection early during pregnancy may increase the risk of miscarriage. OverviewParvovirus B19 infection typically does not cause symptoms or causes mild illness, such as flu-like symptoms, rashes, and joint pa...